The Dry Eye Zone

Rebecca's Blog


Abstract: Nasal steroid spray for allergic rhinitis patients with dry eye

This is a small pilot study only, so don't get too excited, but I thought it was interesting. They found that OSDI scores improved, with the nasal steroid treatment though clinical clinical measurements were unchanged (Schirmer, TBUT, IOP)

Int Arch Allergy Immunol. 2018 May 7:1-6. doi: 10.1159/000488599. [Epub ahead of print]
A Pilot Study Investigating the Impact of Topical Nasal Steroid Spray in Allergic Rhinitis Patients with Dry Eye.
Yenigun A, Elbay A, Dogan R, Ozturan O, Ozdemir MH.

The aim of this study is to demonstrate the effect of nasal steroid treatment on intraocular pressure and dry eye in allergic rhinitis patients with dry eye.

Twenty-nine patients with a diagnosis of allergic rhinitis and dry eye were included. Symptoms and findings of patients before and after nasal steroid therapy were compared.

Ocular Surface Disease Index scores for dry eye symptoms showed significant improvement after nasal steroid treatment (p = 0.003). In the Schirmer test, no significant change was observed in the right or left eye (p = 0.167 and p = 0.489). For the tear film break-up time, no significant change was observed in the right or left eye (p = 0.076 and (p = 0.170). No significant change was observed in the right eye or the left eye in an intraocular pressure test (p = 0.893 and p = 0.495).

In our study, symptoms of dry eye with allergic rhinitis were significantly improved with nasal steroid therapy, without affecting the intraocular pressure.