The Dry Eye Zone

Rebecca's Blog


Abstract: FD-OCT measurement of tear meniscus

Tear meniscus ain't everything, not by a long shot, but still... those who complain their eyes feel the same 5 minutes after putting in drops could understandably be tempted to think this explains how they feel.

Serial Measurement of Tear Meniscus by FD-OCT After Instillation of Artificial Tears in Patients With Dry Eyes.

To use Fourier-domain optical coherence tomography (FD-OCT) to study the effect of artificial tears on the tear meniscus in patients with dry eyes.

The lower tear meniscus of 16 consecutive patients with dry eyes was imaged by an FD-OCT system (RTVue; Optovue, Inc., Fremont, CA). Baseline and five serial pairs of measurements were taken after the instillation of artificial tears (Optive; Allergan, Irvine, CA) at 1, 2, 5, 10, and 15 minutes. The lower meniscus height, depth, and area were measured with a computer caliper.

Baseline meniscus measurements were 235.5 ± 150.0 μm, 138.1 ± 78.7 μm, and 0.020 ± 0.022 mm(2) for height, depth, and area, respectively. After instillation of artificial tears, all lower tear meniscus parameters remained significantly elevated for 5 minutes and returned to baseline by 10 minutes.

FD-OCT is able to quantify a dramatic initial increase in tear meniscus, followed by a decay back to baseline values after approximately 5 minutes. FD-OCT may be useful in objectively quantifying the dynamic efficacy of dry eye treatments.

Ophthalmic Surg Lasers Imaging. 2011 Jul-Aug;42(4):308-13. doi: 10.3928/15428877-20110603-02.
Bujak MC, Yiu S, Zhang X, Li Y, Huang D.