The Dry Eye Zone

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Abstract: Demodex and chronic blepharitis

Just a case study, but thought it might be of interest to those following the Demodex connection potential.

[Chronic blepharitis: which role for Demodex folliculorum? A case report.]
Ann Biol Clin (Paris). 2009 Nov-Dec;67(6):701-4.
[Article in French]
Martinaud C, Gaillard T, Pons S, Fournier B, Brisou P.
Service de dermatologie, Fédération des laboratoires HIA Sainte Anne, Toulon.

We present a 73-year-old woman presented to our hospital with a 2 years history of eyes itching. The ophthalmological testing was normal. Physical examination revealed blepharitis and lesions acnea-like on mouth, nose and chest. Biological testing revealed no abnormalities. Histologic study and direct immunofluorescence on a cutaneous biopsy were no contributive. The research of an allergic origine was practised by cutaneous and serological tests and negative. An examination of eyelashes was performed and yielded Demodex. Demodex folliculorum is a mite that is the most common permanent ectoparasite of humans, which is thought to be linked to blepharitis and allergic blepharoconjunctivis with rosacea, although much controversy persists. Recent studies demonstrate a high frequence of chronic blepharitis when Demodex are abundant. Several molecules can be used to treat this infestation. Parasiticide as oral ivermectine may be useful when the infestation is important.