The Dry Eye Zone

Rebecca's Blog


Abstract: Ointment in a special case

Ectro-WHAT? My goodness.

As you all know, I officially hate ointments (personally and scientifically) with the exception of Muro 128 for ABMD (though I think Dwelle is a lot more effective). I'm convinced that for the vast majority of dry eye patients there are better options including better lubricants and moisture chambers. But at the end of the day, I'm just a dumb patient. And if they can prove something really does help someone and does not hurt them more than it helps, well and good.

Management of evaporative dry eye in ectrodactyly-ectodermal dysplasia-clefting syndrome.
Optom Vis Sci. 2008 Sep;85(9):E795-801. Links
Ota Y, Matsumoto Y, Dogru M, Goto E, Uchino Y, Endo K, Tsubota K.

PURPOSE: The purpose of this study is to report the features of dry eye and ocular surface disease in an unusual case of ectrodactyly-ectodermal dysplasia-clefting (EEC) syndrome.

CASE REPORT: A single observational case report of a 22-year-old Japanese male with evaporative dry eye and corneal epithelial disease because of lipid layer abnormality resulting from meibomian gland agenesis was treated successfully with low dose lipid base ointment application.

DISCUSSION: The clinical features of the dry eye and ocular surface disease and management issues are discussed.

CONCLUSION: Low dose lipid base ointment application may be a promising treatment modality for the ocular surface disease in ectrodactyly-ectodermal dysplasia (EEC)-clefting syndrome, which seems to help in alleviating the subjective complaints and in improving the objective clinical findings.