The Dry Eye Zone

Rebecca's Blog


Study: Stevens-Johnson Syndrome.

Paints a grim picture. I'm puzzled as to why there is no mention of either bandage contacts or Boston sclerals. I'm not too knowledgeable about the former but the latter at least have well documented benefits for SJS. Why resort to surgery if you don't have to?

The ophthalmologic management of acute stevens-johnson syndrome.
Gregory DG.
Ocul Surf. 2008 Apr;6(2):87-95.

ABSTRACT Stevens-Johnson syndrome (SJS) and its more severe variant, toxic epidermal necrolysis (TEN), cause significant ocular surface damage. The majority of affected patients develop conjunctival inflammation during the acute phase of the disease. If intense, this inflammation yields permanent destruction of the normal mucosal tissue of the ocular surface and eyelids. Loss of the normal glandular structures leads to severe dry eye problems and vision loss. Medical treatments do little to arrest these problems, and repairing the damage after the acute phase is difficult, if not impossible. Recently, the application of cryopreserved amniotic membrane to the ocular surface during the acute phase of the disease has shown great promise in limiting the destructive inflammation and its long-term sequelae. A rationale for this treatment and a detailed description of the application procedure are provided, along with practical guidelines for the managing surgeon.