The Dry Eye Zone

Rebecca's Blog


New drug news: Re-inspired.

You've got to hand it to them for persistence. Prolacria is not going away, at least not yet.

Inspire tries again with dry eye drug

The News & Observer, Oct 20 2007

Inspire Pharmaceuticals hired a Massachusetts company to test its troubled dry-eye drug, Prolacria.

The medicine has been in regulatory limbo since it failed the second of four clinical trials two years ago.

Prolacria has been tested on 2,000 patients with mixed results. After talks with the Food and Drug Administration, Inspire said in a regulatory filing that it will test the effectiveness of the drug in a particular part of the eye.

Inspire has agreed to pay Ophthalmic Research Associates of North Andover, Mass., up to $34.5 million if the test results get Prolacria regulatory approval.