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    Thread: Fetzima

    1. #1

      Fetzima

      Hello,

      There's a new antidepressant coming out later this year - called Fetzima (levomilnacipran).
      Fetzima is a chemical cousin of Savella (Milnacipran)
      Fetzima is only approved for treatment of Major Depression.

      Link to Fetzima:
      https://fetzima.com

      Savella is only approved for treatment of fibromyalgia.
      http://www.savella.com

      Not sure how much better Fetzima will be over other SNRIs like Cymbalta

      here's the specs about it in comparison to other SNRIs (and, see attached paper)
      Venlafaxine - has a 30-fold greater specificity for serotonin than norepinephrine
      Cymbalta - has a 10 fold greater specificity for serotonin than norepinephrine
      Milnacipran(Savella) - has a 1:1 relationship regarding serotonin and norepinephrine (prefers each the same ratio)
      Levomilnacipran (fetzima) has a 1:2 relationship between preferring serotonin and norepinephrine, respectively.

      Link to abstract about Fetzima -
      http://www.ncbi.nlm.nih.gov/pubmed/23499664
      Attached Files Attached Files

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