Freshkote is Dwelle plus a phospholipid ingredient. Just to clarify on the FDA approval status... My understanding is that FreshKote is compliant with the over-the-counter requirements (there is no "approval" or testing process for OTC eyedrops - instead they have a list of requirements they have to comply with) and the laws permit OTC products to be sold on a prescription basis by the choice of the company. Just mentioning to clarify it doesn't mean FreshKote is not FDA compliant, but rather that they haven't pursued FDA approval as an Rx drug.
Dwelle isn't made anymore. I'm an unabashed diehard fan of Dr. Holly's drops, and though I think of FreshKote as not quite as good as Dwelle, I'd still (personally) prefer it over other OTC drops.
Rebecca Petris
The Dry Eye Zone