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Fetzima

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  • Fetzima

    Hello,

    There's a new antidepressant coming out later this year - called Fetzima (levomilnacipran).
    Fetzima is a chemical cousin of Savella (Milnacipran)
    Fetzima is only approved for treatment of Major Depression.

    Link to Fetzima:
    https://fetzima.com

    Savella is only approved for treatment of fibromyalgia.
    http://www.savella.com

    Not sure how much better Fetzima will be over other SNRIs like Cymbalta

    here's the specs about it in comparison to other SNRIs (and, see attached paper)
    Venlafaxine - has a 30-fold greater specificity for serotonin than norepinephrine
    Cymbalta - has a 10 fold greater specificity for serotonin than norepinephrine
    Milnacipran(Savella) - has a 1:1 relationship regarding serotonin and norepinephrine (prefers each the same ratio)
    Levomilnacipran (fetzima) has a 1:2 relationship between preferring serotonin and norepinephrine, respectively.

    Link to abstract about Fetzima -
    http://www.ncbi.nlm.nih.gov/pubmed/23499664
    Attached Files
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