KeratoScoop (Rebecca's blog)

This is a duplicate of my Dry Eye Digest blogspot blog - to see the full archives back to 2005, please click on that link.

  1. Abstract: Comparing PF vs BAK-preserved glaucoma meds

    You all know my soapbox! Thankfully, more and more doctors are paying attention to those glaucoma medication side effects (including the fact that dry eye side effects may cause patients to be less compliant) and more preservative-free options are coming on the market.

    This study compares efficacy of an unpreserved glaucoma drop (Catioprost) versus a popular BAK-preserved one (Xalatan).

    A Comparative Study of a Preservative-Free Latanoprost Cationic Emulsion (Catioprost(®)) and a BAK-Preserved Latanoprost Solution in Animal Models. ...
    Tags: bak
    Categories
    Recent studies
  2. Abstract: Autologous serum drops versus artificial tears

    Autologous serum drops are being used more and more. There have been a great many more sophisticated studies of what it does - this is just a simple one showing how serum drops relieve symptoms better than artificial tears.

    Randomized Double-Blind Clinical Trial of Autologous Serum versus Artificial Tears in Dry Eye Syndrome.
    Purpose:
    To determine symptoms improvement in dry eye patients with short-term autologous serum (AS) eyedrops treatment using the standardized
    ...
    Categories
    Recent studies
  3. Abstract: InflammaDry in detecting MMP-9

    The Practical Detection of MMP-9 Diagnoses Ocular Surface Disease and May Help Prevent Its Complications.
    PURPOSE:
    To evaluate the importance and practicality of testing for matrix metalloproteinase 9 (MMP-9) in dry eye and ocular surface disease. This enzyme, which can cause tissue damage, seems also to be the most reliable diagnostic indicator of ocular surface disease.
    METHODS:
    Enzyme-linked immunosorbent assay, polymerase chain reaction, diffusion, and InflammaDry,
    ...
    Tags: inflammadry
    Categories
    Recent studies
  4. Abstract: Azasite and Doxy - comparing what they do (or don't) for MGs

    Topical Azithromycin and Oral Doxycycline Therapy of Meibomian Gland Dysfunction: A Comparative Clinical and Spectroscopic Pilot Study.
    PURPOSE:
    Meibomian gland dysfunction (MGD) is a common clinical problem that is often associated with evaporative dry eye disease. Alterations of the lipids of the meibomian glands have been identified in several studies of MGD. This prospective, observational, open-label clinical trial documents the improvement in both clinical signs and symptoms
    ...
    Categories
    Recent studies
  5. Abstract: Anti-inflammatory effects of ALA on epithelial cells

    Anti-inflammatory Effects of Alpha Linolenic Acid on Human Corneal Epithelial Cells.
    Purpose:
    Systemic polyunsaturated fatty acids (PUFAs) were shown to improve the symptoms of dry eye syndrome due to their anti-inflammatory effects. This study evaluated the in-vitro anti-inflammatory effects of PUFAs on human corneal epithelial (HCE) cells.

    Methods:
    HCE cells were incubated for 2 hours with different concentrations of PUFAs: Alpha-linolenic acid (ALA), Gamma-linolenic
    ...
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