When I first received my free samples of Dwelle and Dakrina I found they stung my eyes severely. However I was not one to give up easily and I do not like wasting drops, so I thought I would put Dwelle in before I showered. It worked brilliantly - the shower soothed my sore eyes and I found I could go without drops for longer and my eyes were more comfortable. It really helps before going out. I have found that my eyes do not sting now unless I am having a bad day. I always use Dwelle before a shower and it is good therapy :) at any time of the day if the eyes feel bad.