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Goblet cells

Mucus-secreting cells in the corneal epithelium and conjunctival epithelium


The mucin layer of the tear film plays a critical role in healthy tears and a healthy ocular surface, therefore there is considerable interest in the goblet cells which produce it. In many patients with dry eye, it has been shown that goblet cells are less dense. Goblet cell density is also one measure of the efficacy of dry eye treatments.



links and references

ABSTRACT: Ocular Surface Management of Photorefractive Keratectomy and Laser in situ Keratomileusis, Julie M. Albietz, PhD; Suzanne G. McLennan, BAppSc(Optom); Lee M. Lenton, FRANZCO, FRACS Jour Refr Surg 19:6  Nov/Dec 2003.

ABSTRACT: Goblet cell density in ocular surface disease. A better indicator than tear mucin. S. Kinoshita, T. C. Kiorpes, J. Friend and R. A. Thoft. Arch Ophthalmol Vol. 101 No. 8, August 1983.

ABSTRACT: Conjunctival goblet cell densities in ocular surface disease. Nelson JD, Wright JC. Arch Ophthalmol. 1984 Jul;102(7):1049-51.

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